Trending Now: Is Facebook Staring at its ‘Orkut’ Moment? How Valentine’s Day Came to Be Using Ecobricks to Make Artificial Rocks
Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors

Non-Caloric Sweeteners: A Boon or A Bane

Madhumita Neog | January 23, 2022

Users must moderate the consumption of non-caloric sweeteners to alleviate terminal damage to vital organs. 

Non-Caloric Sweeteners: A Boon or A Bane

Decades ago, the introduction of non-caloric sweeteners aimed to reduce caloric intake without compromising on taste. Ironically, the surge in consumption of these artificial sweeteners failed to control the rise in weight gain, diabetes and cardiovascular diseases.

Widely used as a replacement for sugar without raising glycaemia, the use of non-caloric sweeteners can be linked to short term weight reduction. However, prolonged use of non-caloric sweeteners like aspartame and sucralose can adversely impact body composition and metabolism by damaging the liver.

In the initial stages, findings in nutrition research indicated that the impact of non-caloric sweeteners with increased hepatic lipogenesis created more fat storage in the adipose tissues.

Due to its intense sweetness, the caloric signals associated with sweetness and satiety get disrupted. As a result, over a period of time, our body goes into an energy saving mode. The challenge here is that although these sweeteners can trick the sweet taste receptor sites, they cannot elicit satiety signals.

Chronic high doses are now being linked to impaired glucose tolerance and increased inflammation in the body. Changes in the gut microbiota have also been observed due to increases in a highly gluconeogenic substrate. Moreover, links of short chain fatty acids to insulin resistance and inflammation have been found.

Side effects of long-term use of non-caloric sweeteners

Excessive use of non-caloric sweeteners could be a suspect in inflicting damage to organs, especially the liver by causing oxidative stress, increase in pro-inflammatory cytokines and production of free radicals.

Five artificial sweeteners and one low calorie sweetener have been approved by the Food and Drug Administration. But we still don’t know how these can impact the human body and brain. More research is needed to establish the safety of artificial sweeteners.

Despite the artificial intelligence on artificial sweeteners, whether or not the benefits will outweigh the risks will all depend on how much is actually safe, and at what cost to health.

The bottom line is that if you are not sure about how many cans of diet soda you can consume in day, always remember that you can’t possibly go wrong with a bottle of water and an apple!


Madhumita Neog

Madhumita is a certified nutritionist with over 10 years of experience in this domain. Certified by VLCC, India, Stanford University and the University of Edinburgh, she believes in leading by example. She is the founder of Mountain Feet Nutrition and her clientele includes super models, artists and professional athletes too.


Madhumita was the Fitness Ambassador in Fit Expo India 2019 and is a proud recipient of the International Women Achiever’s Award by the Press Club of India in 2019. Apart from being a lifestyle coach and weight management specialist, she is also a pageant trainer and an adventure buff who pursues high altitude trekking as a hobby.


She had damaged her left knee on one of her treks and battled spinal injuries too but her passion for fitness and trekking remains undeterred. She is also a philanthropist helping backward communities in Sundarbans.

Notify of
Inline Feedbacks
View all comments
Would love your thoughts, please comment.x